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| Effection of Ginsenoside Re on ADP, PAF, AA-induced platelet aggregation |
| Hits 2775 Download times 2410 Received:May 07, 2016 |
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| DOI
10.11656/j.issn.1673-9043.2016.05.07 |
| Key Words
ginsenoside Re;platelet aggregation;ADP;PAF;AA |
| Author Name | Affiliation | E-mail | | YAN Hai-feng | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | DAI Xiang-dong | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | FAN Ke-tao | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | WANG Yi | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | vip-wangyi@126.com |
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| Abstract
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| [Objective] To study the effect of ginsenoside Re on platelet aggregation function.[Methods] In vitro, through the Born law, effect of ginsenoside Re on sodium salt adenosine diphosphate (ADP), platelet-activating factor (PAF), arachidonic acid (AA)-induced platelet aggregation rate of.[Results] Ginsenoside Re in vitro ADP, PAF, AA-induced platelet aggregation was statistically significant difference (P<0.05, P<0.01), median inhibiting concentration (IC50), 0.197 g/L, 0.242 g/L, and 0.443 g/L respectively.[Conclusion] The ginsenoside Re in a dose-dependent inhibition of in vitro ADP, PAF, AA-induced platelet aggregation, and ADP-induced platelet aggregation was stronger than PAF, AA. |
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