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Isolation and structural identification of constituents from Dioscoreae spongiosae Rhizoma
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DOI   10.11656/j.issn.1673-9043.2016.05.13
Key Words   Dioscoreae spongiosae Rhizoma;chemical constituents;structural identification
Author NameAffiliationE-mail
CHAO Li-ping Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China  
RUAN Jing-ya Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China  
LIU Yan-xia Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China  
HAN Li-feng Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China  
WANG Tao Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China  
ZHANG Yi Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China zhwwxzh@263.net 
Abstract
    [Objective] Study on chemical constituents of Dioscoreae spongiosae Rhizoma.[Methods] The chemical constituents were obtained by ODS, Sephadex LH-20 and PHPLC chromatorgraphy isolation, and identified by chemical and spectral analysis.[Results] The structures of seven comounds were elucidated to be tachioside (1), isotachioside (2), koaburaside (3), 2, 6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (4), icariside D2 (5), benzyl alcohol O-β-D-glucopyranoside (6), and adenosine (7), respectively.[Conclusion] Compounds 1~3 were obtained from Dioscoreae genus firstly, and 4~7 was isolated from the plant for the first time.

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