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| Simultaneous identification of 20 components in Xuebijing injection by UPL——TO-MS/MS |
| Hits 1789 Download times 3019 Received:January 03, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2017.03.13 |
| Key Words
Xuebijing injection;UPLC-Q-TOF-MS/MS;qualitative analysis |
| Author Name | Affiliation | E-mail | | TU Ya-ru | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | OUYANG Hui-zi | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | SUN Meng-jie | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | CHANG Yan-xu | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | HE Jun | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | hejun673@163.com |
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| Abstract
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| [Objective] To develop a UPLC-Q-TOF-MS/MS method for simultaneous identification of 20 components in Xuebijing injection.[Methods] The method of qualitative analysis was performed on ACQUITY UPLC®BEH C18(2.1 mm×100 mm,1.7 μm) column with a gradient mobile phase system of acetonitrile and 0.1% formic acid.All of the analytes were identified in negative ionization.According to the high resolution MS spectra data,fragmentation ion information andretention time,20 peaks were identified by comparison with reference standards data.[Results] Twenty components were identified in 45 min.[Conclusion] The established method for the identification of chemical constituents in Xuebijing injection is simple and accuracy. |
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