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| The intervention effect of Daixiefang on the patients of metabolic syndrome with dyslipidemia, insulin resistance |
| Hits 1377 Download times 1319 Received:April 04, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2017.04.06 |
| Key Words
metabolic syndrome;dyslipidemia;insulin resistance;Daixiefang;phlegm and blood stasis |
| Author Name | Affiliation | E-mail | | LI Chen-ying | Shanghai Hospital of Traditional Chinese Medicine and Western Medicine of Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China | | | CHEN Zhao-shan | Affiliated Hospital of Traditional Chinese Medicine of Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | 821337580@qq.com | | HU Jian-wen | Affiliated Hospital of Traditional Chinese Medicine of Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | YU Juan | Affiliated Hospital of Traditional Chinese Medicine of Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | LUO Yun | Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China | |
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| Abstract
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| [Objective] To evaluate the intervention effect and safety of Daixiefang, and to elaborate the advantages and prospects of compound traditional Chinese medicine preparation in the treatment of metabolic syndrome associated with dyslipidemia and insulin resistance (phlegm and blood stasis type).[Methods] Sixty-two cases of metabolic syndrome patients associated with dyslipidemia were randomly divided into Daixiefang group, Xuezhikang group, and Daixiefang plus Xuezhikang group. The clinical effective rate, blood lipid, insulin resistance, pancreatic β-cell function, as well as integral of the symptoms were observed in three groups. In the end, it was established a database and analyzed the data by statistical software SPSS 21.0.[Results] No side-effect (liver and kidney damage) was found during the trail. Triglycerides, total cholesterol, LDL, Fasting glucose, Homa-IR of the three groups after treatment were reduced significantly (P<0.05) Daixiefang plus Xuezhikang group acted effectively on decreasing laboratory indicators than the other two groups. Integral of the symptoms of MS was also decreased significantly (P<0.05).[Conclusion] Daixiefang plus Xuezhikang group is better than Xuezhikang group in lipids and symptoms. In summary, Daixiefang is effective in patients of MS with dyslipidemia. |
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