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An effect analysis on clinical system of infertility which caused by Kuntai capsule on reducing the ovarian reserve
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DOI   10.11656/j.issn.1673-9043.2017.04.07
Key Words   Kuntai capsule;ovarian reserve function;curative effect analysis
Author NameAffiliationE-mail
LIU Yu-lan Department of Traditional Chinese Medicine, Affiliated Hospital of Chengde Medical University, Chengde 067000, China  
GAO Hui Department of Traditional Chinese Medicine, Affiliated Hospital of Chengde Medical University, Chengde 067000, China gaohuihbcd@163.com 
XIA Tian Department of Infertility, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
MA Rui-hong Department of Infertility, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
Abstract
    [Objective] To compare the curative effect of diminished ovarian reserve for infertility patients between Kuntai capsule and dehydroepiandrosterone (DEHA).[Methods] 108 DOR patients were randomly divided into 2 groups. The treatment group 55 cases took Kuntai capsule 4 tablets each time, 3 times a day and monitored their menstrual cycle for 3 months continuous. 53 patients in control group were given DHEA for 1 tablet each time, 3 times a day and compare the total score of TCM syndrome at different time with various clinical symptoms.[Results] Kuntai capsule can significantly improve the syndrome total score. After 2-3 months treatment, both syndrome score has no significant change. But treatment group has significantly decreased. Difference between treatment and groups were both significant (P>0.05). With the extension of treatment time, the improvement is more obvious. The improvement of symptomatic characteristics is also different, such as speed of onset, hot flashes, night sweats, exhausted, dizziness, tinnitus and other symptoms, after 1 month treatment, the curative effect in Kuntai group is obvious better than DHEA group, the difference was statistically significant(P<0.05). After 3 month's treatment, most of the clinical symptoms improvements are more obvious. The effect of the treatment group was significantly better than that of DHEA group, and the difference was statistically significant (P<0.05).[Conclusion] Kuntai capsule can improve the clinical symptoms of patients with DOR as well as patients life qualities. It efficient is much better than DHEA which needs further research and popularization.

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