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| Advances in mechanism studies on estrogen-like effect of Salvia miltiorrhiza Bge. |
| Hits 2678 Download times 1560 Received:April 21, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2017.05.02 |
| Key Words
Salvia miltiorrhiza Bge.;estrogen-like effect;mechanism |
| Author Name | Affiliation | E-mail | | GUO Ao-wei | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | | | PU Wei-ling | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | | | LUO Ying-ying | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | | | BAI Ru-yu | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | | | SHI Hong | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | | | ZHOU Kun | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | | | GAO Xiu-mei | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | gaoxiumei@tjutcm.com | | SUN Li-kang | Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of pharmacology of Chinese Materia Medica, Tianjin 300193, China | likang.sun@bluewin.ch |
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| Abstract
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| Salvia miltiorrhiza Bge. is a kind of classical traditional Chinese medicine for promoting blood-system circulation by promoting the blood-system circulation to remove blood stasis and to regulate the menstruation, and by cooling the blood-system to remove carbuncle and tranquilization. It's showed that the pharmacological effects of Salvia miltiorrhiza Bge., in the related experimental research and clinical application. Salvia miltiorrhiza Bge. and its active ingredients were similar to those of phytoestrogens, which were widely used in therapy of gynecological disease, such as breast cancer and hyperplasia of mammary glands, through regulation of ER, promoting cell apoptosis or other pathway. |
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