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| Isolation and identification of glycosides from the leaves of Nelumbo nucifera Gaertn. |
| Hits 2627 Download times 1590 Received:May 10, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2017.05.13 |
| Key Words
Nelumbinis Folium;glycosides;chemical constituents;structure identification |
| Author Name | Affiliation | E-mail | | WANG Hao | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | XIA Ming-hui | Cangzhou central hospital, Cangzhou, Tianjin 061000, China | | | PANG Xu | Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | HAN Li-feng | Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | hanlifeng_1@sohu.com | | ZHANG Yan-jun | Office of Academic Affairs, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | zyjsunye@163.com |
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| Abstract
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| [Objective] To investigate the glycosides from the lotus leaf in order to further research on quality control and new drug development.[Methods] The glycosides were separated by silica gel, ODS, Sephadex LH-20 column chromatographies, as well as preparative HPLC, the structures were identified by MS, NMR spectra and comparison with literatures.[Results] Nine compounds were purified from 70% ethanol extract of lotus leaves and identified as isoquercitrin (1), quercetin-3-O-β-D-xylopyranosyl(1→2)-β-D-galactopyranoside (2), quercetin-3-O-β-D-glucuronide-6"-methyl ester (3), quercetin-3-O-β-D-glucuronide-6"-ethyl ester (4), kaempferol 3-O-β-D-galactopyranoside (5), chrysoeriol-7-O-β-D-glucopyranoside (6), chrysoeriol-7-O-β-D-glucopyranoside (7), (+)-pinoresinol-4-O-β-D-glucoside (8), (+)-epipinoresinol-4'-O-β-D-glucoside (9).[Conclusion] Compounds 3, 4, 8 and 9 were obtained from genus of Nelumbo for the first time. |
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