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Application of LC-MS in the research of traditional Chinese medicine prescriptions |
Hits 1612 Download times 1151 Received:August 31, 2017 |
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DOI
10.11656/j.issn.1673-9043.2017.05.19 |
Key Words
traditional Chinese medicine compound preparation;LC-MS;pharmacodynamics;pharmacokinetics;quality control;rational administration |
Author Name | Affiliation | E-mail | QI Kun | The University of Traditional Chinese Medicne, Tianjin 300193, China The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | WANG Yang | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | dayang810025@163.com | CHEN Tao | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | shkk_001@163.com | LI Jin | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | |
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Abstract
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Liquid chromatography-mass spectrometry (LC-MS) technology has become a powerful method for the modernized research of traditional Chinese medicine preparations because of its high separation performance, high sensitivity and strong specificity. LC-MS is widely used of analysis the chemical composition, serum pharmacochemistry, pharmacodynamics, pharmacokinetics, quality control of traditional Chinese medicine preparations, and the phenomenon of illegal addition of chemical components in traditional Chinese medicine preparations. |
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