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Shengmai powders for patients with myocardial infarction:a systematic review
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DOI   10.11656/j.issn.1673-9043.2017.06.10
Key Words   Shengmai powers;myocardial infarction;randomized controlled trial;systematic review
Author NameAffiliationE-mail
SHI Xiao-ting Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
LI Bin The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China xxlibin2006@163.com 
ZHAO Ting-kai Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
MU Biao Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
CAO Ru-mei Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
LI Xue-song Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
REN Yu-xiu Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
LI Jie Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
CHEN Hui Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
ZHANG Jin Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
Abstract
    [Objective] To evaluate the clinical therapeutic effect of western medicine plus Shengmai powers versus simple western medicine in myocardial infarction (MI) patients.[Methods] We systematically searched the CNKI, CBM, VIP, Wanfang, PubMed, Cochrane Library, Web of science and other related periodicals to identify randomized controlled trials(RCTs). The quality of studies was evaluated according to methods of the Cochrane Collaboration, the data were extracted; and meta-analyses were performed with RevMan5.3.0 soft ware.[Results] Eleven trials involving 766 patients were included. The results of meta-analyses showed that compared with the simple western medicine treatment, the combination of western medicine and Shengmai powers therapy significantly improved the symptoms, clinical comprehensive effect[OR=2.82,95% CI(1.57,5.50),P=0.000 5], reduce the incidence of cardiovascular events after myocardial infarction[OR=0.29,95% CI(0.15,0.54),P=0.000 1], reduce the plasma endothelin level[MD=-16.69,95% CI(-24.79,-8.60),P<0.000 1].[Conclusion] The therapeutic effect of combining western medicine with Shengmai powers therapy on myocardial infarction patients is better than that of simple western medicine treatment.

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