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Study on the chemical constituents of Scorzonera mongolica Maxim.
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DOI   10.11656/j.issn.1673-9043.2017.06.17
Key Words   Scorzonera mongolica Maxim.;chemical constituents;structure identification
Author NameAffiliationE-mail
YAN Yan Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
ZHAO Jing Tianjin Binhai New Area Traditional Chinese Medicine Hospital, Tianjin 300450, China  
SUN Lei Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
GUO Jiang-yu Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
YU He-shui Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China hsyu@tjutcm.edu.cn 
LI Wei Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
ZHANG Li-juan Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China lijuanzhang63@163.com 
SONG Xin-bo Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
Abstract
    [Objective] To study the chemical component of Scorzonera mongolica Maxim.[Methods] The chemical compounds were isolated through ODS, sephadex LH-20, silicagel column chromatorgraphies and PHPLC chromatorgraphy and identified by chemical and spectral analysis.[Results] Nineteen monomeric compounds were isolated and identified from the 95% ethanol extract of Scorzonera mongolica Maxim.:3-O-ferulylquinic acid methyl ester (1), 3-O-ferulylquinic acid (2), 4-O-ferulylquinic acid (3), dihydrocaffeic acid (4), dihydrocaffeic acid n-butyl ester (5), dihydrocaffeoy acid ethyl ester (6), dihydrocaffeic acid methyl ester (7), caffeic acid (8), 3,5-dimethoxy-4-hydroxy benzoic acid ethyl ester (9), vanillin (10), 1'-O-vanillinacyl-β-D-glycosidase(11),5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one(12), 2-(3, 4-dihydroxyphenyl)-5, 7-dihydroxy-chromen-4-one(13), 3β-hydroxyl-5α, 8α-epidioxyergosta-6, 22-diene (14), β-sitosterol (15), β-daucosterol (16), 1-linoleic acid monoglyceride (17), linolenic acid (18), palmitic acid (19).[Conclusion] Compounds 1~3 were isolated from the plant for the first time.

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