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| An overview of pathogenesis and biological basis in phlegm and blood stasis of coronary heart disease |
| Hits 2036 Download times 1626 Received:June 15, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2018.01.01 |
| Key Words
intermin-gled phlegm and blood stasis;atherosclerosis;lipid metabolism;inflammation mediators;polymorphism |
| Author Name | Affiliation | E-mail | | YAN Dandan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | bianyuhong_2012@163.com | | BIAN Yuhong | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YU Chunquan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | ycq-4@163.com |
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| Abstract
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| In recent years, due to the high morbidity and serious lesion of intermin-gled phlegm and blood stasis syndrome of CHD, people are paying more attention to it. By reading the literature, we reviewed the possible biological basis of phlegm stasis syndrome from etiology, pathogenesis, lipid metabolism, inflammatory mediators, homocysteine and gene polymorphism. Preliminary studies determined that the formation of intermin-gled phlegm and blood stasis syndrome including yin and yang deficiency, spleen-stomach transportation-metabolism disability, liver dysfunction, the stagnation of phlegm turbidity and retained fluid. AS is the result of interaction of many factors, and is one of the pathological bases for the formation of CHD, AS and myocardial ischemia are particularly likely to show pathological factors such as phlegm turbidity and congestion. This article will overview the pathogenesis and biological basis of intermin-gled phlegm and blood stasis syndrome from traditional Chinese medicine and western medicine, so as to provide guidance for clinical syndrome differentiation. |
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