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| Experimental study on the analgesic and sedative effects of Wuwei Jiangya formula |
| Hits 1486 Download times 1117 Received:August 25, 2017 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2018.01.14 |
| Key Words
Wuwei Jiangya formula;analgesic;sedative |
| Author Name | Affiliation | E-mail | | LI Xueli | Beijing University of Chinese Medicine, Beijing 100029, China | | | WANG Wei | Beijing University of Chinese Medicine, Beijing 100029, China | | | WANG Peipei | Beijing University of Chinese Medicine, Beijing 100029, China | | | GONG Ming | Beijing University of Chinese Medicine, Beijing 100029, China | | | DENG Dong | Beijing University of Chinese Medicine, Beijing 100029, China | | | LI Shaojing | Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China | | | REN Yinglu | Beijing University of Chinese Medicine, Beijing 100029, China | | | MA Xueling | Beijing University of Chinese Medicine, Beijing 100029, China | | | ZHAO Huihui | Beijing University of Chinese Medicine, Beijing 100029, China | hh686@126.com |
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| Abstract
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| [Objective] To study the analgesic and sedative effects of Wuwei Jiangya formula.[Methods] Writhing method and heat stimulation method were used to observe the analgesic effect. Tail-hanging test was used to observe the sedative effect of Wuwei Jiangya formula on mice.[Results] The results showed that Wuwei Jiangya formula at medium dose could significantly reduce writhing times of mice. Low dose treatment for 90 min and high dose treatment for 30 min and 90 min could significantly increase mice pain thresholds. Meanwhile, high dose for 120 min extended 5 min tail-hanging immobility time of mice.[Conclusion] Certain dose of Wuwei Jiangya formula may play a role in analgesia and sedation. |
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