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| The research progress about MSCs transplant of osteoporosis |
| Hits 1450 Download times 1159 Received:September 04, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2018.01.20 |
| Key Words
osteoporosis;MSCs;transplantation |
| Author Name | Affiliation | E-mail | | AI Juqing | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | MAO Haoping | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | haoping_mao@126.com |
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| Abstract
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| Until now anti-osteoporosis drug researches mainly focus on the balance about bone resorption with formation, while little research about the relation about MSCs number and function(migration, homing, differentiation) with osteoporosis. Osteoblast and adipocyte both derived from MSCs,therefore when MSCs is impaired, which resulting that osteoblasts function decreases, and adipocyte number increases, and the bone mass losses, finally caused osteoporosis. MSCs transplant could increase bone mass and density, and it would became new methods to cure osteoporosis. |
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