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| The influence on substance and energy metabolism, endocrine system and autonomic nervous system of fraction of Scutellaria baicalensis in normal rats |
| Hits 1563 Download times 1339 Received:October 13, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2018.02.12 |
| Key Words
the fraction of Scutellaria baicalensis;cold and warm property;substance metabolism;energy metabolism;endocrine system;autonomic nervous system |
| Author Name | Affiliation | E-mail | | ZHANG Yanan | Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | CHEN Pingping | Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | WANG Hongyu | Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | GAO Xin | Drug Safety EvaluationCenter, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | LIU Shumin | Drug Safety EvaluationCenter, Heilongjiang University of Chinese Medicine, Harbin 150040, China | keji-liu@163.com |
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| Abstract
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| [Objective] To illuminate the cold and warm property of fraction of Scutellaria baicalensis by detecting related enzyme expression in substance metabolism, energy metabolism, endocrine system and autonomic nervous system in normal rats.[Methods] Fifty male SD rats were randomly divided into blank control group, total composition group, aglycone group, glycosides group, polysaccharide group; All groups were gavaged for 15 days, taking the liver, heart, muscle and detecting the relevant index.[Results] Compared with the blank group, the total composition group of Scutellaria baicalensis can inhibit substance metabolism, energy metabolism, endocrine system and autonomic nervous system, aglycones and glycosides have the the similar trend with the cold medicine polysaccharide group has no obvious tendency.[Conclusion] Overall, the total composition group of Scutellaria baicalensis has cold property and confirm the cold property once again;at the same time we can infer that aglycones and glycosides have cold property and they are the main material basis of Scutellaria baicalensis cold property; polysaccharide has a little cold property and we need to do deep research. |
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