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| The antibacterial activity of total Flavonoids in Bidensbipinnata |
| Hits 1415 Download times 1088 Received:December 17, 2017 |
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| DOI
10.11656/j.issn.1673-9043.2018.03.16 |
| Key Words
Bidensbipinnata;flavonoids;minimum inhibitory concentration;Staphylococcus aureus;Pseudomonas aeruginosa |
| Author Name | Affiliation | E-mail | | CAO Mingchen | Shandong University of Traditional Chinese Medicine, Jinan 250355, China | | | FANG Mengxiang | Shandong University of Traditional Chinese Medicine, Jinan 250355, China | | | HUANG Xin | Shandong Qianfoshan Hospital, Jinan 250014, China | 13791120711@126.com |
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| Abstract
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| [Objective] To study the in vitro antibacterial activity of Bidensbipinnata to Staphylococcus aureus, Escherichia coli, Candida albicans and Pseudomonas aeruginosa.[Methods] The total flavonoids were extracted by 50% ethanol-petroleum ether-ethyl acetate and purified by macroporous resin AB-8 column chromatography. The drug susceptibility of bacteria of total flavonoids was measured by disk diffusion method, the minimum inhibitory concentration (MIC) was determined by afar dilution method.[Results] The total flavonoids of Bidensbipinnata were less sensitive to Escherichia coli and had a certain inhibitory effect on Candida albicans, Pseudomonas aeruginosa and Staphylococcus aureus.[Conclusions] The total flavonoids of Bidensbipinnata showed inhibitory effects on a variety of bacteria, suggesting that there may be a broad antibacterial spectrum. |
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