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Correct understanding of “Asarum's dose can not exceed one qian”
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DOI   10.11656/j.issn.1673-9043.2018.05.04
Key Words   Asarum;dosage;toxicity;pharmacology
Author NameAffiliationE-mail
WANG Li Shandong University of Traditional Chinese Medicine, Jinan 250014, China  
WU Bo Hospital of Traditional Chinese Medicine of Shandong Province, Jinan 250014, China wubojinan@163.com 
WANG Shaoyin Linzi Maternal and Child Health Hospital of Zibo City, Zibo 255400, China  
Abstract
    [Objective] Discuss the origin of "Asarum's dose can not exceed one qian" and its rationality to guide the clinical safety and effective use of Asarum.[Methods] Through the analysis of the ancient herbal literature, the clinical symptoms of Asarum poisoning, the pharmacological study of Asarum and the actual effect of clinical observation, put forward a reasonable understanding of "Asarum's dose can not exceed one qian".[Results]"Asarum's dose can not exceed one qian" original meaning is that in the case of powder alone, the dose can not exceed 3.125 g to avoid poisoning life-threatening.In the compound decoction Asarum can not only more than 3.125 g, if necessary, medication can be large doses or too large doses.[Conclusion] By selecting a reasonable boiling time and appropriate compatibility, can enhance the efficacy of Asarum and reduce the side effects. Asarum can be overused when clinical use containing Asarum decoction, according to the specific circumstances of the patient.

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