|
| A systematic review of the efficacy and safety of Gynecologic Qianjin tablets in the treatment of chronic pelvic inflammatory disease |
| Hits 1776 Download times 1196 Received:June 05, 2018 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2018.05.19 |
| Key Words
Gynecologic Qianjin tablets;Chronic pelvic inflammatory disease;system evaluation;randomized controlled trial |
| Author Name | Affiliation | E-mail | | QIN Yishan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | SHI Bolun | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YU Jisen | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YANG Fengwen | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | ZHENG Wenke | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | zhengwk@tice.com.cn | | ZHANG Junhua | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | |
|
| Abstract
|
| [Objective] To systematically evaluate the effectiveness and safety of Gynecologic Qianjin tablets in the treatment of chronic pelvic inflammatory disease, seven databases were searched for studies on the safety and effectiveness of Gynecologic Qianjin tablets.[Methods] Search database of CNKI, WF, VIP, SinoMed, Pubmed, EMbase, The Cochrane Library, collect about Gynecologic Qianjin tablets randomized controlled trials for the treatment of chronic pelvic inflammatory disease. Retrieval time limit are built from the library until February 2017. Two evaluators independently selected trials, extracted data, cross-checked and methodological quality assessments.Statistical analysis was performed using RevMan version 5.3 software.[Results] Eventually included 12 RCTs, a total of 1 291 patients with chronic pelvic inflammatory disease. Meta analysis showed that:1) Gynecologic Qianjin tablets can significantly improve the total effective rate of chronic pelvic inflammatory disease,(RR=1.21, 95% CI[1.15, 1.27]),2) Gynecologic Qianjin tablets can significantly relieve chronic pelvic inflammatory uterine lift pain,[MD=-4.33,95% CI(-4.91,-3.75),P<0.000 01],3) Gynecologic Qianjin tablets significantly improved abdominal pain chronic pelvic inflammatory disease,[MD=-4.09,95% CI(-4.35,-3.69),P<0.000 01],4) Gynecologic Qianjin tablets significant improvement for abnormal vaginal discharge,[MD=-3.40,95% CI(-5.07,-1.74),P<0.000 01],5)Adverse reactions:Mainly including rash, mouth bitter astringent, nausea and vomiting. There is no statistically significant.[Conclusion] The existing study shows that the total effective rate of chronic pelvic inflammatory disease of Gynecologic Qianjin tablets compared with the control group was significantly improved, the pain of chronic pelvic inflammatory uterine lift significantly improved. And no obvious adverse reactions. Because this system evaluates the inclusion of RCTs for low-quality, small sample studies, more high-quality studies are needed to further validate their efficacy. |
|
|
|
|
|
