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| Research on the analysis method of “Organization & Compatibility Network of TCM Prescription”-Based on outpatient prescription data from famous doctors of TCM |
| Hits 1775 Download times 1745 Received:October 22, 2018 |
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| DOI
10.11656/j.issn.1673-9043.2019.01.01 |
| Key Words
Organization & Compatibility Network of TCM Prescription;data mining;rule of prescription;association rules;Complex Network Analysis |
| Author Name | Affiliation | | WANG Dong | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | WANG Yimin | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | ZHANG Boli | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the feasibility of applying the Analysis Method,which is based on “Organization & Compatibility Network of TCM Prescription”,to study the inherent compatibility rules of experts' outpatient prescriptions.[Methods] Three hundred and sixty-nine outpatient prescriptions for the treatment of thoracic obstruction were obtained from a related expert. According to the inclusion and exclusion criteria,qualified prescriptions were selected and the required data were extracted. Under the guidance of traditional Chinese medicine theory,comprehensive use of complex network analysis,association analysis methods,mining the expert's thoughts of prescriptions and specific probability of compatibility,build the “Organization & Compatibility Network of TCM Prescription” and its core group,summed up the prescription inherent compatibility laws. Through the comparison of different network models,verified by the relevant literature,the Analysis Method of “Organization & Compatibility Network of TCM Prescription” is feasible.[Results] The “Organization & Compatibility Network of TCM Prescription” and its core group can reflect the expert's thoughts of prescriptions and specific probability of compatibility. Based on the node's Betweenness Centrality,the key drugs can be selected. The links and communities formed by the key nodes can reflect the theory and therapy based on TCM. Verified by the literature,the results,which obtained by using the Analysis Method of “Organization & Compatibility Network of TCM Prescription”,accord with the expert academic thoughts and compatibility of medicines.[Conclusion] The “Organization & Compatibility Network of TCM Prescription” can not only reflect the expert's thoughts of prescriptions,but also provide the compatibility witch supported by data. It can be used as a basic method for experts' outpatient prescriptions data mining. |
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