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| Compound danshen dropping pill combined three statins system evaluation for the treatment of coronary heart disease angina pectoris |
| Hits 1577 Download times 1374 Received:June 28, 2018 |
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| DOI
10.11656/j.issn.1673-9043.2019.01.14 |
| Key Words
compound danshen dropping pill;statins;system evaluation;meta-analysis |
| Author Name | Affiliation | E-mail | | LIU Xuan | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin fourth central hospital, Pharmacy, Tianjin 300143, China | | | YANG Fengwen | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Ting | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Xiaoying | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | wxy@tjutcm.edu.cn |
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| Abstract
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| [Objective] To assess the clinical efficacy of danshen dropping pill combined with statin in the treatment of the heart of coronary heart disease.[Methods] To search the CNKI,WanFang Data,SinoMed PubMed,Cochrane Library,Embase database using compound danshen drop pill combined with statins in the clinical randomized controlled trial study of coronary heart disease angina pectoris,no language restriction. The quality of the study was analyzed by using the Cochrane Handbook 5.3 recommendation of bias risk assessment tool.[Results] 21 literatures were included in the standard,and the results of meta-analysis showed that clinical symptoms:heterogeneity test I2=44%,P=0.02),[RR=1.20,95%CI (1.16,1.25)]. ECG:heterogeneity test I2=28%,P=0.19,(RR=1.36,95%CI (1.25,1.48)]. Lipid levels improve:cholesterol heterogeneity test I2=8%,P=0.36,(MD=0.81,95%CI (0.98,0.63)],low density protein (LDL) heterogeneity test I2=86%,P=0;The heterogeneity test of platelet aggregation rate I2=94%,P=0.[Conclusion] Compound danshen dropping pill combined with three statins has obvious advantages in improving clinical symptoms and improving ecg ischemia. |
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