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Research progress on optimization of t-PA thrombolytic therapy for stroke |
Hits 1790 Download times 1046 Received:October 20, 2018 |
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DOI
10.11656/j.issn.1673-9043.2019.01.24 |
Key Words
Stroke;t-PA thrombolysis;optimization methods |
Author Name | Affiliation | E-mail | TANG Weiwei | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | XIONG Ke | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | LI Nan | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | WANG Shuang | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | YU Yajun | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | YAN Yiqi | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | ZHANG Han | Biology Department of Institute of traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | zhanghan0023@126.com |
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Abstract
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Stroke has become a major cause of death and disability today.Tissue plasminogen activator (t-PA) therapy is currently the most effective treatment for strokeHowever,t-PA narrow treatment time window and its treatment after thrombolytic reperfusion may cause complications such as bleeding transformation,re-infarction,and reperfusion injury,not all patients can get good results after t-PA thrombolytic therapy.Therefore,we need to study new drugs or treatments to improve t-PA thrombolytic therapy.This article will review the methods of optimizing thrombolytic therapy for t-PA in recent years. |
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