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| Research progress of biomarkers in sepsis |
| Hits 1856 Download times 918 Received:September 30, 2018 |
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| DOI
10.11656/j.issn.1673-9043.2019.01.25 |
| Key Words
SIRS;sepsis;non-infection SIRS;biomarker |
| Author Name | Affiliation | E-mail | | TONG Xiaofang | Tianjin University of Tradition Chinese Medicine, Tianjin 300193, Chinan | | | CUI Yuanlu | Tianjin University of Tradition Chinese Medicine, Tianjin 300193, Chinan | cuiyl@tju.edu.cn |
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| Abstract
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| Systemic inflammatory response syndrome (SIRS) is a common complication in critically ill patients. According to the pathogenesis,it can be divided into infection SIRS (sepsis) and non-infection SIRS. It is difficult to distinguish sepsis and non-infection SIRS because of the similar clinical manifestations. At present,the mortality caused by SIRS is relatively high because of the unspecific diagnostic criteria anduntargeted clinical treatment. There are many biomarkers studied for early diagnosis and prognosis of sepsis. Biomarkers,such as procalcitonin,Lipopolysaccharides receptor and cytokine,showed good specificity and sensitivity in the diagnosis,identification and prognosis of sepsis,which possessedgreat help in clinical treatment of sepsis. In this paper,several sepsis biomarkers were reviewed. |
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