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Pregnancy outcomes after the treatment of intrauterine adhesion by traditional Chinese medicine combined with artificial cycle: a meta analysis
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DOI   10.11656/j.issn.1673-9043.2019.02.13
Key Words   combination of Chinese and western medicine;artificial cycle;uterine adhesion;randomized controlled trial;meta-analysis
Author NameAffiliationE-mail
ZHANG Miaomiao Foshan Chancheng Central Hospital, Foshan 582000, China  
GAO Jie The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China  
XI Yuantang Foshan Chancheng Central Hospital, Foshan 582000, China  
DENG Gaopi The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China denggaopi@126.com 
Abstract
    [Objective] To explore the pregnancy pregnancy rate and clinical effect of traditional Chinese medicine combined with artificial cycle in treating uterineadhesion.[Methods] The computer searched Pubmed,Embase,Cochrane Library,CNKI,Wan Fang,VIP etc. We selected literature according to inclusion and exclusion criteria.After evaluating the quality of the included studies and extracting the data,a Meta-analysis was perfomed by using RevMan 5.3.[Results] 15 RCTs were involved in 1 035 patients. Meta analysis showed that the combination of traditional Chinese medicine and artificial cycle could significantly increase the pregnancy rate after intrauterine adhesions surgery. Clinical effectiveness,menstrual recovery were significantly higher than those in the control group. Combination of traditional Chinese and Western medicine treatment group can reduce intrauterine adhesions postoperative intrauterine adhesion score,endometrial spiral artery index,and resistance index,the difference was statistically significant. The endometrial thickness and abortion rate between the two groups were not statistically significant.[Conclusion] the pregnancy rate,clinical efficiency,menstrual recovery and endometrial thickness of Chinese medicine combined with artificial cycle in the treatment of intrauterine adhesions are superior to artificial cycle,and can reduce the intrauterine adhesion score,PI and RI index.

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