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| Research progress on the quantitative analysis of chemical constituents in Epimedium herb and its pharmacokinetics |
| Hits 1551 Download times 1585 Received:February 11, 2019 |
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| DOI
10.11656/j.issn.1673-9043.2019.03.04 |
| Key Words
Epimedium;chemical constituents;analysis method;pharmacokinetics;research progress |
| Author Name | Affiliation | E-mail | | OUYANG Huizi | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | HE Jun | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin State Key Laboratory of Modern Chinese Medicine, Co-construction of Province and Ministry, State Key Laboratory Breeding Base, Tianjin 301617, China | hejun673@163.com |
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| Abstract
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| Epimedium herb, as a traditional herb medicine for tonifying Kidney Yang, had a long history of use in Chinese medicine. Our paper had reviewed the relevant literature of chemical analysis and pharmacokinetics of Epimedium. It was found that Epimedium contained many active constituents (such as flavonoids, alkaloids, phenolic acids and so on), and its active constituents were differently affected by many factors such as cultivars, place of production, medicinal site, and processing. The bioavailability of various components of Epimedium in vivo was different, and the pharmacokinetics was differently affected by many factors such as disease, prescription compatibility, processing, and drug interaction. According to the summary of quantitative analysis of active constituents in Epimedium and the pharmacokinetic properties, some problems existed in the present research had been discussed to provide a reference for the quality control, drug development and clinical application of Epimedium herb. |
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