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Advances in animal models of heart failure
Hits 2030  Download times 1230  Received:May 19, 2019  
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DOI   10.11656/j.issn.1673-9043.2019.06.05
Key Words   heart failure;animal models;production methods
Author NameAffiliationE-mail
HUANG Ming Tianjin University of Traditional Chinese Medicine, Tianjin 300617, China  
XIONG Ke Tianjin University of Traditional Chinese Medicine, Tianjin 300617, China  
LI Xiao Tianjin University of Traditional Chinese Medicine, Tianjin 300617, China  
LV Ling Tianjin University of Traditional Chinese Medicine, Tianjin 300617, China  
LI Lin Tianjin University of Traditional Chinese Medicine Research Institute, Key Laboratory of Pharmacy, Ministry of Education, Tianjin 300617, China  
ZHANG Han Tianjin University of Traditional Chinese Medicine Research Institute, Key Laboratory of Pharmacy, Ministry of Education, Tianjin 300617, China zhanghan0023@126.com 
Abstract
    Heart failure is a common cardiovascular syndrome, its morbidity and mortality increased year by year, serious harm to human health. The pathogenic factors of heart failure are complex, but the research on the pathogenesis and intervention therapy of heart failure is far from meeting the clinical requirements. In this paper, the methods and principles of heart failure models commonly used in the literature in recent years are summarized, and their advantages and disadvantages are compared.

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