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| The research on different extraction methods of total flavonoids of the aerial part of Glycyrrhiza uralensis and the antioxidant activity of total flavonoids |
| Hits 1632 Download times 1535 Received:December 24, 2019 |
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| DOI
10.11656/j.issn.1673-9043.2020.02.06 |
| Key Words
the aerial parts of Glycyrrhiza uralensis;total flavonoids;extraction method;antioxidant activity |
| Author Name | Affiliation | E-mail | | BO Yingyi | School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China | | | ZHANG Yuehui | School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China | | | YANG Liu | School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China | | | CUI Jie | Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China | | | WANG Wenquan | School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Engineering Research Center of GAP for Chinese Crude Drugs, Ministry of Education, Beijing 100102, China | | | HOU Junling | School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China
Engineering Research Center of GAP for Chinese Crude Drugs, Ministry of Education, Beijing 100102, China | mshjl@126.com |
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| Abstract
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| [Objective] To compare different extraction methods to extract total flavonoids from the aerial parts of Glycyrrhiza uralensis and the antioxidant activity of total flavonoids. [Methods] The extraction rate of total flavonoids in the aerial parts of Glycyrrhiza uralensis is chosen as a an evaluation indicator. The influence of different extraction solvents and different extraction methods to the extraction rate is examined. Moreover,the in vitro antioxidant activity is assessed by the scavenging capacity of DPPH and the reducing power of the aerial parts of Glycyrrhiza uralensis. [Results] By comparison,the best extraction methods and extraction solvent are determined to be the ultrasonic extraction or reflux extraction,and methanol,respectively. Meanwhile,the total flavonoids obtained performs well in both the scavenging capacity of DPPH and the reducing power,demonstrating certain dose-effect relationship. [Conclusion] Our research indicates that the antioxidant activity of total flavonoids in the aerial parts of Glycyrrhiza uralensis is worthy of the further investigation,and lays a foundation for the comprehensive exploitation and utilization of Glycyrrhiza uralensis in medicine and food industry. The antioxidant activity of Glycyrrhiza uralensis can be gradually and widely applied in many other relevant areas. |
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