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| Clinical observation of Shugan Jianpi Yangxin Decoction in the treatment of chronic hepatitis B patients （liver depression and spleen deficiency type） |
| Hits 1394 Download times 2040 Received:September 15, 2019 |
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| DOI
10.11656/j.issn.1673-9043.2020.02.10 |
| Key Words
Shugan Jianpi Yangxin Decoction;chronic hepatitis B;liver depression and spleen deficiency type;clinical observation |
| Author Name | Affiliation | E-mail | | SU Kaiqi | Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | LIN Liubing | Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | CHEN Yirong | Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | YAN Ni | Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | LI Yong | Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | liyong_sci@126.com |
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| Abstract
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| [Objective] To observe the clinical efficacy and safety of Shugan Jianpi Yangxin Decoction in the treatment of CHB patients (liver depression and spleen deficiency type). [Methods] A total 72 chronic hepatitis B patients (liver depression and spleen deficiency type) were divide into two groups. Thirty six patients in the treatment group were treated with Shugan Jianpi Yangxin Decoction and 36 cases in the control group were treated with Shugan Jianpi Decoction for 12 weeks. These scores of TCM syndrome,SF-36 quality of life scale score and biochemical indexes of the two groups before and after treatment were observed and recorded,and the clinical efficacy and safety were evaluated. [Results] As for the overall effect of TCM symptoms,the total effective rate of treatment group is 94.44%,and the control group is 75.00%. SF-36 quality of life scale was improved in both groups after treatment,in terms of physiological function,social function and mental health,the treatment group's effect was better than control group (P<0.05). Liver function was improved after treatment in both groups,but no differences (all P>0.05). Both Decoctions were safe,and no toxic or side effects were found. [Conclusion] Shugan Jianpi Yangxin Decoction can significantly improve the clinical efficacy of chronic hepatitis B patients (liver depression and spleen deficiency type),and it is safe for clinical use and worthy of promotion. |
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