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Clinical observation on the treatment of vulvar white lesion with common cnidium fruit powder combined with oral taking Chinese medicine
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DOI   10.11656/j.issn.1673-9043.2020.02.13
Key Words   common cnidium fruit powder;traditional Chinese medicine fumigation;oral medicinal herbs;vulvar white lesion
Author NameAffiliation
WANG Ziru Taizhou Affiliated Hospital of Nanjing University of Traditional Medicine, Taizhou Hospital of Traditional Chinese Medicine, Taizhou 225300, China 
REN Qingling Chinese Medicine Hospital of Jiangsu Province, Nanjing 210029, China 
ZHAO Yue The Northern Jiangsu People's Hospital, Yangzhou 225000, China 
Abstract
    [Objective] To observe the clinical curative effect of cnidium fruit powder fumigation and washing of vulva in combination with oral taking Chinese medicine in treating vulvar white lesion. [Methods] Clinical observation of 80 cases of perimenopausal vulvar hypopigmentation patients with syndrome of liver-kidney yin deficiency based on traditional Chinese medicine. The patients were randomly divided into groups according to the order of treatment:the treatment group used tonifying liver and kidney herbs orally and cnidium fruit powder fumigation and washing of vulva. The vulva washing method is applied daily in the morning and evening in the premenstrual period. It is a course of treatment every 4 weeks,and is discontinued during menstruation. 3 consecutive courses of treatment. The control group was given topical application of western medicine triamcinolone ointment for 3 months. Follow-up was performed at 6 months and 12 months to observe the short-term effect,long-term effect,and clinical symptom score before and after treatment. [Results] The treatment group was cured in 12 cases (30%),markedly effective in 22 cases (55%),improved in 4 cases (10%),and ineffective in 2 cases (5%). The recent total effective rate was 95%,and the follow-up was 12 months. There were 34 cases and 6 cases of recurrence. The total long-term effective rate was 85%. The control group was cured in 10 cases (25%),markedly effective in 17 cases (42.5%),improved in 6 cases (15%),ineffective in 7 cases (17.5%),and the total effective rate in the near future was 82.5%. Followed up for 12 months,25 cases were effective,15 cases recurred,and the total long-term effective rate was 62.5%. There was no statistical difference in the near-term efficiency between the two groups,and there was a statistical difference between the long-term efficiency. The long-term efficiency in the treatment group was significantly higher than that in the control group.The clinical symptoms before and after treatment were significant,the difference was statistically significant,and the improvement of symptoms in the treatment group was better than that in the control group. [Conclusion] Cnidium fruit powder Fumigation and Washing of Vulva combined with traditional Chinese medicine orally tonifying liver and kidney,is an accurate,safe and non-invasive treatment method,which is worthy of further clinical application.

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