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Systematic evaluation on the improvement of angina pectoris with Shexiang Tongxin Dropping Pills combined with conventional Western medicine
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DOI   10.11656/j.issn.1673-9043.2020.02.16
Key Words   Shexiang Tongxin Dropping Pills;coronary heart disease;angina pectori;Meta-analysis
Author NameAffiliationE-mail
DU Huiqing Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LIU Zhichao Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
HUANG Yuhong Department of Cardiology, Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300150, China  
WANG Baohe Department of Cardiology, Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300150, China wbh3423@sina.com 
Abstract
    [Objective] Based on the meta-analysis,the improvement and efficacy of Shexiang Tongxin Dropping Pills combined with conventional Western medicine for coronary heart disease and angina pectoris were systematically evaluated. [Methods] Computer retrieval CNKI,Wang Fang,Wei Pu (VIP),the Chinese biomedical literature database (CBMdisc),PubMed and EMbase database published about Shexiang Tongxin Dropping Pills combination with conventional Western medicine treatment of angina pectoris and coronary heart disease convalescence randomized controlled clinical trial (RCT) research before November 2019,and evaluate the quality and effective information extraction,using Cochrane RevMan5.3 software for statistical analysis. [Results] Eleven qualified RCT studies were included,there were 1075 subjects,including 540 in the test group and 535 in the control group. The result of meta-analysis showed that,compared with conventional Western medicine treatment alone,the addition of Shexiang Tongxin Dropping Pills could further reduce the number of angina pectoris attacks in angina pectoris patients (P<0.01),angina duration (P<0.01). [Conlusion] Compared with conventional Western medicine in the treatment of coronary heart disease and angina pectoris,Shexiang Tongxin Dropping Pills combined with conventional Western medicine can improve the curative effect one step at a time. However,in view of the limitation in quantity and quality of included clinical studies,the result is only used as evidence-based reference for clinical diagnosis and treatment,and more high-quality RCT is needed to further confirm the curative effect.

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