|
| Effects of Qidi Tangshen Formulation in treating DKD patients with microalbuminuria and its effects on urine PCX and LAP |
| Hits 1361 Download times 1437 Received:February 10, 2020 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2020.03.09 |
| Key Words
microalbuminuria;Qidi Tangshen Formulation;diabetic kidney disease;urine PCX;urine LAP |
| Author Name | Affiliation | E-mail | | XU Jing | Beijing University of Chinese Medicine, Beijing 100029, China | | | LIU Hongfang | Dongzhimen Hospital, Beijing University of Chinese Medicine Beijing 100700, China | lhfdoctor@126.com | | MIAO Guizhen | Tongzhou District of Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 101121, China | | | CAO Bailong | Tongzhou District of Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 101121, China | | | LI Xia | Dongzhimen Hospital, Beijing University of Chinese Medicine Beijing 100700, China | | | YU Borui | Beijing University of Chinese Medicine, Beijing 100029, China | | | WANG Dan | Beijing University of Chinese Medicine, Beijing 100029, China | | | LIAN Xinyi | Beijing University of Chinese Medicine, Beijing 100029, China | |
|
| Abstract
|
| [Objective] To study the clinical effect of Qidi Tangshen Formulation on microalbuminuria and its influence on urine PCX and LAP in type diabetic kidney disease with qi-yin deficiency and blood stasis and heat blocking collaterals.[Methods] Sixty patients of DKD with deficiency of both qi and yin and obstruction of blood stasis and heat were randomly divided into the two groups. The treatment group received basic treatment (lowering blood sugar,lowering blood pressure,lowering blood lipid and diet guidance) and Qidi Tangshen Formulation,while the control group received basic treatment and placebo. The clinical curative effect,traditional Chinese medicine syndrome curative effect and the change of urine ACR,blood sugar,blood fat,urine PCX and urine LAP were compared between the two groups.[Results] The total effective rate of the treatment group was significantly higher than that of the control group (P<0.05). The total effective rate of TCM syndrome integral in treatment group was significantly higher than that in control group (P<0.05). The difference of ACR and LAP in urine of the treatment group was significantly different from that of the control group (P<0.05).[Conclusion] Qidi Tangshen Formulation has a significant effect on DKD patients with qi-yin deficiency and blood stasis and heat blocking collaterals,which can reduce urine protein and urine LAP. |
|
|
|
|
|
