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Research progress on chemical constituents of guaiacolide-type Sesquiterpenes from Centipeda minima
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DOI   10.11656/j.issn.1673-9043.2020.04.21
Key Words   Centipeda minima;sesquiterpenes;guaiactone
Author NameAffiliationE-mail
SHI Rui Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 301617, China  
HE Mingshuai Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 301617, China  
LYU Jialin Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 301617, China  
WANG Rongrong Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 301617, China  
JIANG Miaomiao Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 301617, China miaomiaojiang@126.com 
Abstract
    Centipeda minima, also known as herba centipedae, is a traditional Chinese midicinal plant. The results show that Centipeda minima contains a large number of guaiactone sesquiterpenes and has anti-allergic, anti-inflammatory and anti-tumor activities. In this paper, the chemical structures characteristics and pharmacological activities of 33 sesquiterpenes isolated and identified from Centipeda minima were summarized in order to provide a reference basis for more rational utilization of plant resources of Centipeda minima.

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