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| Systemic prevention and treatment of acute graft-versus-host disease by integrated traditional Chinese and Western medicine |
| Hits 1041 Download times 743 Received:January 03, 2020 |
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| DOI
10.11656/j.issn.1673-9043.2020.04.22 |
| Key Words
acute graft-versus-host disease;integrated traditional Chinese and Western medicine;immunosuppressive;attacking evil spirits;supporting the righteousness |
| Author Name | Affiliation | E-mail | | ZHU Hongyan | Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Modern Chinese Medicine, Tianjin 301617, China
Tianjin International Joint Academy of Biomedicine, Research and Development Center of TCM, Tianjin 300457, China | | | FENG Yuxin | Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Modern Chinese Medicine, Tianjin 301617, China
Tianjin International Joint Academy of Biomedicine, Research and Development Center of TCM, Tianjin 300457, China | fengyn@live.com |
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| Abstract
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| Acute graft-versus-host disease (aGvHD) threats the survival of allogeneic hematopoietic stem cell transplantation recipients. It is key to prevent cytokine storm from triggering severe immune responses and tissue damage to recipients. This review summarizes the integrative interventions of aGvHD,including the effects of natural immunosuppressants (such as triptolide and matrine) combining with classic immunosuppressants cyclosporine A in the prevention and treatment of aGvHD. It is indicated that combining immunosuppressive therapies with traditional Chinese medicine may prevent the occurrence and development of aGvHD. Therefore,we advocate a strategy for the prevention and treatment of aGvHD by integrated Chinese and western medicine,and hope to provide some new ideas for alleviating transplant complications. |
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