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| Research progress of integrated traditional Chinese and Western medicine in the treatment of primary bile cirrhosis |
| Hits 1039 Download times 1198 Received:June 22, 2020 |
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| DOI
10.11656/j.issn.1673-9043.2020.05.23 |
| Key Words
primary biliary cirrhosis;traditional Chinese medicine;research progress |
| Author Name | Affiliation | E-mail | | CHEN Jing | Department of Hepatology, Guanganmen Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100053, China | | | LI Juanmei | Department of Hepatology, Guanganmen Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100053, China | | | LYU Wenliang | Department of Hepatology, Guanganmen Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing 100053, China | lvwenliang@sohu.com |
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| Abstract
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| Primary bile cirrhosis (PBC) is a chronic bile stasis autoimmune liver disease that occurs mainly in intralobular bile duct cells. The incidence rate of the population is 4 to 30 cases during 10 000 people per year,and the number of deaths account for 1.6% to 2.0% of the total number of patients with liver cirrhosis. The mechanism of the PBC is not clear,which is mainly believed to be related to autoimmunity. Ursodeoxycholic acid is commonly used in western medicine,but the effect is poor. In recent years,it has been reported that traditional Chinese medicine combined with UDCA has been used in the treatment of PBC,and some curative effects have been obtained. This paper mainly reviews the research progress of clinical treatment of PBC in recent 5 years from the aspects of etiology and pathogenesis and traditional Chinese medicine treatment. At the same time,it points out the defects existing in the current research of integrated traditional Chinese in the treatment of PBC and looks forward to the future research. |
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