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| Effect of Bailing Capsule combined with α-Keto acid tablets on nutritional status and quality of life in patients with CKD3-4 stage of chronic kidney disease |
| Hits 1230 Download times 830 Received:August 10, 2020 |
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| DOI
10.11656/j.issn.1673-9043.2020.06.11 |
| Key Words
Bailing Capsule;α-keto acid tablets;chronic kidney disease;nutritional status;quality of life |
| Author Name | Affiliation | E-mail | | ZHENG Xin | Longhua Hospital Renal Pathology Department Subsidiary to Shanghai Traditional Chinese Medicine University, Shanghai 200320, China | | | CHEN Yi | Longhua Hospital Renal Pathology Department Subsidiary to Shanghai Traditional Chinese Medicine University, Shanghai 200320, China | | | DENG Yueyi | Longhua Hospital Renal Pathology Department Subsidiary to Shanghai Traditional Chinese Medicine University, Shanghai 200320, China | sh_dengyueyi@163.com。 |
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| Abstract
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| [Objective] To investigate the effect of Bailing Capsule combined with α-keto acid tablets on nutritional status and quality of life in patients with chronic kidney disease CKD3-4.[Methods] Ninetycases of chronic kidney disease CKD3-4 patients admitted to Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine from March 2018 to June 2019 were selected as the research subjects,and randomly divided into control group,Bailing Capsule group and test group,30 cases each. The control group was given dietary control to regulate blood pressure,blood lipids,and blood sugar;to improve acid-base imbalances and electrolyte disorders,to correct anemia,and other conventional treatments,the Bailing Capsule group added Bailing Capsules to the control group. The experimental group added α-keto acid tablets on the basis of the Bailing Capsule group and continued treatment for 3 months. The treatment efficiency,renal function level,malnutrition score and quality of life score of the three groups were compared.[Results] The total effective rate of treatment in the experimental group was significantly higher than that in the control group(P<0.05),the difference was statistically significant;serum creatinine,urea nitrogen,and uric acid in the Bailing Capsule group and the experimental group were lower than before treatment,and eGFR was higher than before treatment High,comparing creatinine,eGFR,blood uric acid(P<0.05),the difference was statistically significant. After treatment,the albumin,prealbumin,and hemoglobin in the Bailing Capsule group and the experimental group were higher than before treatment,and the malnutrition score was lower than before treatment. The albumin,prealbumin,hemoglobin,and malnutrition scores were compared between groups(P<0.05),the difference is statistically significant. The improvement of quality of life after treatment in the experimental group was better than that before treatment(P<0.05),the difference was statistically significant;comparing the quality of life scores of the three groups after treatment between the three groups(P<0.05),the difference was statistically significant.[Conclusion] Bailing Capsules combined with α-keto acid tablets can effectively improve the renal function and nutritional status of patients,improve the quality of life of patients,delay the progression of disease,and are worth clinical promotion. |
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