|
| Study on the treatment of advanced malignant tumor with hypercoagulable state by Chinese herbal medicine combined with low molecular weight heparin calcium |
| Hits 1273 Download times 776 Received:August 03, 2020 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2020.06.13 |
| Key Words
self-made prescription of traditional Chinese medicine;advanced malignancy;hypercoagulable state;low molecular weight heparin |
| Author Name | Affiliation | | HAN Jinfeng | Wuqing Traditional Chinese Medicine Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China | | ZHANG Haoyue | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | LIU Chunxiang | Wuqing Traditional Chinese Medicine Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China | | ZHANG Wenjie | Wuqing Traditional Chinese Medicine Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China | | DU Guoqiang | Wuqing Traditional Chinese Medicine Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China | | SONG Shasha | Wuqing Traditional Chinese Medicine Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China | | WANG Han | Wuqing Traditional Chinese Medicine Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China |
|
| Abstract
|
| [Objective] To observe the clinical effects and safety of the combination of self-made prescription of traditional Chinese medicine (TCM) and low molecular weight heparin calcium for the treatment of hypercoagulable state of advanced malignant tumors.[Methods] A total of 70 patients with hypercoagulable state of advanced malignant tumors were selected and randomly divided into the control group (low molecular weight heparin calcium) and the test group (self-made prescription of TCM and low molecular weight heparin calcium),with 35 patients in each group. Blood platelet,fibrinogen,D-dimer,TCM blood stasis syndrome score,Karnofsky performance status (KPS) and safety indicators of patients in the two groups were observed before and after treatment for 14 days.[Results] The blood platelet,fibrinogen,D-dimer,blood stasis syndrome score andKPS score of the two groups after treatment were all better than those before treatment,and those in the test group were better than those of the control group,and differences between these two group were statistically significant (P<0.05). One patient in the control group had small amount of gingival bleeding,and no adverse reactions occurred in the test group.[Conclusion] The combination of self-made prescription of TCM with low molecular weight heparin calcium can better improve the patients with hypercoagulable state of advanced malignant tumors,which is better than the simple treatment with low molecular weight heparin calcium. |
|
|
|
|
|
