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| Research progress on the chemical constituents and pharmacological activities of Forsythiae fructus |
| Hits 1069 Download times 909 Received:October 03, 2020 |
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| DOI
10.11656/j.issn.1673-9043.2021.02.07 |
| Key Words
Forsythiae fructus;phillyrin;antiviral effect |
| Author Name | Affiliation | E-mail | | QI Lina | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | CHEN Xuanhao | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | JIN Hua | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Jin | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | HE Jun | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | CHANG Yanxu | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | tcmcyx@126.com |
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| Abstract
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| Forsythia suspensa(Thunb.) Vahl. is one of traditional Chinese medicines,which has the function of clearing away heat and detoxification,detumescence,and dispersing wind fever. It has been mainly used as medicinal constituent in the treatment of ulcer,acute mastitis,scrofula,anemopyretic cold,erysipelas,and febrile disease early,high fever with polydipsia,anuria,and coma and so on. There are many chemical components in Forsythia suspense,including phenethyl alcohol glycosides,lignans,phenolic acids,flavonoids,terpenoids and volatile oils,C6-C2 natural alcohols and glycosides. Modern pharmacological studies showed that Forsythiae Fructus has anti-inflammatory,antibacterial,antiviral,antioxidant,liver protection,anti-tumor,immune regulation and other activities. This paper systematically summarizes the chemical composition and pharmacological activity,and provides a scientific basis for the development and utilization of Forsythiae Fructus against the coronavirus disease 2019(COVID-19). |
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