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| Proteomics strategy contributes research progress of traditional Chinese medicine modernization |
| Hits 1037 Download times 605 Received:January 19, 2021 |
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| DOI
10.11656/j.issn.1673-9043.2021.03.02 |
| Key Words
proteomic techniques;traditional Chinese medicine;differences inprotein;mechanism of action;mechanism of toxicity |
| Author Name | Affiliation | E-mail | | JIA Guoxiang | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | DONG Yaqian | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YANG Na | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | QIAN Wenxiu | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YIN Hongqing | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YANG Shenshen | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | shine2099@163.com | | LI Yubo | College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | yaowufenxi001@sina.com |
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| Abstract
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| With the change of disease spectrum and health concept,traditional Chinese medicine (TCM) has become an effective means to prevent and treat diseases. However,due to the complexity of TCM components and the compatibility of multiple TCM ingredients,the mechanism of its efficacy has not been completely defined,and the quality standard and safety evaluation system are not perfect enough,which hinders the modernization process of TCM to a certain extent. Proteomics is a modern science that studies the composition of proteins in biological samples and their changing laws. It pays attention to the integrity and dynamics of research,which is highly consistent with the guiding ideology and scientific connotation of TCM theory. In this paper,the application of proteomics in the study of TCM botany,TCM property,prescription compatibility,TCM syndromes,targets and mechanisms of action of TCM,and safety of TCM in recent years are reviewed,providing new research ideas and methods for the modernization of TCM. |
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