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Research progress of molecular mechanism of skin aging and prevention of skin aging with traditional Chinese medicine
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DOI   10.11656/j.issn.1673-9043.2021.04.06
Key Words   skin;chronological aging;photoaging;ultraviolet;traditional Chinese medicine;mechanism
Author NameAffiliationE-mail
ZHU Shan Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHAO Zhiyue Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
WANG Zijing Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
YANG Yi Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LIU Tao Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
WANG Xiang Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
XIA Qingmei Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHANG Han Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China zhanghan0023@126.com 
LI Nan Traditional Chinese Medicine Research Institute, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China linan20080402@163.com 
Abstract
    Aging is also called senescence, the skin as the largest organ of the human body, its aging is the most direct specific manifestation of human aging. Skin aging is the result of the combined action of endogenous factors and exogenous factors, including chronological aging and photoaging. The two are clinically and histologically different, but they have similar molecular mechanisms. Traditional Chinese medicine (TCM) has the characteristics of safety and small adverse reactions, always plays a positive role in preventing and treating skin aging. This paper mainly introduces the molecular mechanism of photoaging, summarizes the similarities of the molecular mechanism of photoaging and chronological aging, and the research status of preventing skin aging with TCM was also summarized. It provides theoretical support for TCM to prevent skin aging and even overall aging.

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