|
| Effects of processing and compatibility on the content of 11 components and fingerprints of dried ginger-schisandra |
| Hits 898 Download times 558 Received:April 10, 2021 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2021.04.22 |
| Key Words
processing-compatibility;dried ginger-schisandra medicine pair;UPLC;content determination;fingerprint |
| Author Name | Affiliation | E-mail | | SU Min | The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Grade Three-level Laboratory of Traditional Chinese Medicine Preparation/Anhui Province Key Laboratory of Chinese Medicinal Formula/AnHui Engineering Technology Research Center of Modernized Pharmaceutics, Hefei 230601, China
Anhui University of Chinese Medicine, Hefei 230031, China | | | JIANG Yu | The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Grade Three-level Laboratory of Traditional Chinese Medicine Preparation/Anhui Province Key Laboratory of Chinese Medicinal Formula/AnHui Engineering Technology Research Center of Modernized Pharmaceutics, Hefei 230601, China
Anhui University of Chinese Medicine, Hefei 230031, China | | | FAN Lanlan | The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Grade Three-level Laboratory of Traditional Chinese Medicine Preparation/Anhui Province Key Laboratory of Chinese Medicinal Formula/AnHui Engineering Technology Research Center of Modernized Pharmaceutics, Hefei 230601, China
Anhui University of Chinese Medicine, Hefei 230031, China | | | WANG Xiaoli | Anhui University of Chinese Medicine, Hefei 230031, China | | | HONG Yan | Anhui University of Chinese Medicine, Hefei 230031, China | 591940167@qq.com | | WU Deling | Anhui University of Chinese Medicine, Hefei 230031, China | | | HAN Yanquan | The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Grade Three-level Laboratory of Traditional Chinese Medicine Preparation/Anhui Province Key Laboratory of Chinese Medicinal Formula/AnHui Engineering Technology Research Center of Modernized Pharmaceutics, Hefei 230601, China | hyquan2003@163.com |
|
| Abstract
|
| [Objective] Establish the method for determining the content of 11 components and the fingerprint of dried ginger-schisandra, and clarify the influence of the processing-compatibility on the content of the components and the fingerprint of the medicine. [Methods] Dried ginger from different origins was processed into pao ginger by the sand blanching method, the dry ginger and pao ginger are respectively compatible with Schisandra. The UPLC method was used to determine the contents of 11 index components in the samples and analyze the similarity of their fingerprints; cluster analysis and principal component analysis were used to study the differences between drug pairs. [Results] Before and after processing, the content of dried ginger-schisandra medicine pair and the medicine pair of schisandra was quite different. After processing, the content of 5 components in the medicine pair increased, the content of 5 components decreased, and the No. 8-gingerol in dried ginger was detected in the schisandra drug pair; UPLC fingerprints matched a total of 26 common peaks, and the similarity of the common peaks was good, all greater than 0. 94; Cluster analysis and principal component analysis showed that dried ginger-schisandra and pao ginger-schisandra medicine pair can be clearly distinguished. [Conclusion] The UPLC showed that processing and compatibility have different degrees of influence on the index components and fingerprints of the dried ginger-schisandra medicine pair. |
|
|
|
|
|
