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Thunder fire moxibustion for sequelae of pelvic inflammatory disease: clinical efficacy and influence on serum Caspase-3 and sFas
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DOI   10.11656/j.issn.1673-9043.2021.05.11
Key Words   thunder fire moxibustion;sequelae of pelvic inflammatory disease;Caspase-3;soluble factor associated suicide
Author NameAffiliationE-mail
WANG Biyun Department of Obstetrics and Gynecology, Wuhan First Hospital, Wuhan 430000, China  
QIN Qin Department of Obstetrics and Gynecology, Wuhan First Hospital, Wuhan 430000, China qianzhu841417@163.com 
Abstract
    [Objective] To observe the curative effect and influence on serum Caspase-3 and soluble factor associated suicide(sFas) of thunder fire moxibustion for sequelae of pelvic inflammatory disease.[Methods] The 65 cases were randomly divided into control (32 cases) and treatment group (33 cases). The control group was given conventional western medicine. Based on conventional Western medicine, the treatment group was given thunder fire moxibustion. The curative effect was evaluated. The changes of visual analogue scale(VAS), pelvic effusion depth, inflammatory mass diameter, and serum level of tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), Caspase-3 and sFas were compared.[Results] The effective rate in treatment group were higher than in control group(P<0.05). After treatment, VAS score in treatment group was lower than in control group(P<0.05), pelvic effusion depth and inflammatory mass diameter in treatment group were lower than in control group(P<0.05), serum level of TNF-α and CRP in treatment group was lower than in control group(P<0.05), serum level of Caspase-3 in treatment group was higher than in control group(P<0.05), and serum level of sFas in treatment group was lower than in control group(P<0.05).[Conclusion] Thunder fire moxibustion for sequelae of pelvic inflammatory disease had definite clinical effect. It can relieve pain symptom, promote the absorption of pelvic effusion and inflammatory mass, reduce serum level of inflammatory factors, and regulate serum level of Caspase-3 and sFas.

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