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Development trend of structure identification and biological activity of acidic polysaccharides
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DOI   10.11656/j.issn.1673-9043.2021.06.24
Key Words   acidic polysaccharide;separation;structural identification;biological activity
Author NameAffiliationE-mail
LEI Xi Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component Traditional Chinese Medicine, Tianjin 301617, China  
DI Jingrui Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component Traditional Chinese Medicine, Tianjin 301617, China  
FU Zhifei Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component Traditional Chinese Medicine, Tianjin 301617, China  
YANG Miaojie Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component Traditional Chinese Medicine, Tianjin 301617, China  
WANG Zeling Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component Traditional Chinese Medicine, Tianjin 301617, China  
ZHANG Peng Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component Traditional Chinese Medicine, Tianjin 301617, China zhp8270@sina.com.cn 
Abstract
    Acidic polysaccharides are widely distributed in nature and have a variety of biological activities, including antioxidant,anti-inflammatory,immunoregulation,hyperglycemic and antitumor. The biological activity is dependent on its molecular weight,monosaccharide composition,and sugar residue type. However,acidic polysaccharide is a kind of high molecular compound with many branches,complex structure and difficult to identify,which brings great limitations to its research and clinical application. This paper mainly reviewed the separation,structural identification and biological activities of the acidic polysaccharides in recent five years,to provide a theoretical basis for the comprehensive development and utilization of acidic polysaccharides.

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