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| Progress on the pharmacological activity and stability of iridoids from Hedyotis diffusa Willd. |
| Hits 1005 Download times 557 Received:August 12, 2021 |
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| DOI
10.11656/j.issn.1673-9043.2021.06.26 |
| Key Words
Hedyotis diffusa Willd;iridoids;pharmacological activity;stability |
| Author Name | Affiliation | E-mail | | ZHAO Wei | Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China | | | HAO Mimi | Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China | | | SUN Fan | Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China | | | RUAN Jingya | Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China | | | WANG Tao | Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China | | | ZHANG Yi | Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China | zhwwxzh@tjutcm.edu.cn |
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| Abstract
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| To establish a foundation for further development and utilization of Hedyotis diffusa Willd(H. diffusa). The pharmacological activities and stability of iridoids in H. diffusa were investigated and summarized. As one of the traditional Chinese medicine,H. diffusa is rich in iridoids,which have varieties of pharmacological activities such as anti-inflammation,anti-fibrosis,liver protection,and so on. The hemiacetal structure of iridoid leads to poor stability and decreased or changed its pharmacological activity. In this paper,the pharmacological activities and stability of iridoids in H. diffusa reported in recent years were reviewed,which would provide reference for further research, development and utilization of the plant. |
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