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| Research progress of acupuncture regulating AD mitochondrial metabolism |
| Hits 1033 Download times 589 Received:August 08, 2021 |
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| DOI
10.11656/j.issn.1673-9043.2021.06.27 |
| Key Words
acupuncture;mitochondria;energy metabolism;Alzheimer's disease;review |
| Author Name | Affiliation | E-mail | | CHEN Kaiyi | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | KAN Bohong | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | WU Bangqi | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | ZHANG Xiangxiang | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | XU Miao | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | CHEN Fuyan | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | ecfy_2005@163.com |
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| Abstract
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| Alzheimer's disease (AD) is related to mitochondrial energy metabolism. Acupuncture is effective in the treatment of Alzheimer's disease,but its mechanism is still unclear. Starting with energy metabolism disorders related substances such as amyloid beta(Aβ),cytochrome oxidase Ⅳ(COX Ⅳ),glucose metabolism regulatory protein 75 (GRP75) and succinate dehydrogenase (SDH),this review explored the relationship between the onset of Alzheimer's disease and mitochondria,and the effect of acupuncture on energy metabolism disorders related substances of mitochondrial cell,aiming to provide new ideas for future research on acupuncture treatment of Alzheimer's disease. |
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