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| A systematic review of randomized controlled trials on the intervention of moxibustion on subhealth yang deficiency |
| Hits 895 Download times 586 Received:August 30, 2021 |
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| DOI
10.11656/j.issn.1673-9043.2022.01.13 |
| Key Words
moxibustion;yang deficiency;subhealthy;Meta analysis;system review |
| Author Name | Affiliation | E-mail | | WANG Dongjun | School of Health Science and Engineering, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Ying | Tangshan Fengnan Hospital of Traditional Chinese Medicine, Hebei Province, Tangshan 063000, China | | | SUN Xuan | School of Health Science and Engineering, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | GUAN Yuanyuan | School of Health Science and Engineering, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | TIAN Zhikui | School of Health Science and Engineering, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Hongwu | School of Health Science and Engineering, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | tjwanghw55@163.com |
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| Abstract
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| [Objective] To systematically evaluate the effect of moxibustion on the intervention of subhealthy yang deficiency.[Methods] The four Chinese databases of China National Knowledge Infrastructure (CNKI), CQVIP database(VIP), Wanfang database(WANFANG DATA), and the Chinese biomedical literature database service system (SignoMed) were searched for literatures published from in January 2011-December 2019, and the included interventions were randomized controlled trials(RCTs) of moxibustion and Jingui Shenqi Pills treatment for the treatment of yang deficiency. The literature was screened and relevant data were extracted by reading the full text, and the effect sizes were combined for Meta analysis.[Results] A total of 11 RCTs were included to assess the quality of the literature using the Cochrane collaboration's risk of bias assessment tool. Nine articles were rated A(low bias) and two articles were rated B(moderate bias). Meta-analysis showed that the relative risk (RR) of moxibustion in the treatment of subhealthy yang deficiency was 1.37, 95% confidence interval(CI)(1.21, 1.54), P<0.001. The mean difference of yang deficiency constitution transformation score was-0.72, 95% CI(-1.00, -0.45), P<0.001. The standardized mean difference (SMD) for overall health score SMD=1.23, 95% CI(0.17, 2.29), P<0.05. Mean difference of vitality score was 9.37, 95% CI (6.87, 11.87), P<0.001. SMD of physiological function score was 0.90, 95% CI(0.45, 1.34), P<0.001. SMD of somatic pain score was 0.75, 95% CI(0.06, 1.44), P<0.005. The standard mean difference of yang deficiency syndrome score was 0.55, 95%CI(0.18, 0.92), P<0.05). Most of the included studies did not report recurrence rate, quality of life and adverse reactions, and these indicators could not be further analyzed.[Conclusion] Compared with the traditional Chinese medicine Jingui Shenqi Pills for treating yang deficiency, the moxibustion was more efficient in the treatment of subhealthy yang deficiency. However, due to the small quantity and low quality of the included literature, we still need to design a large sample, multi-center and high-quality randomized controlled clinical trial to verify it in the future. |
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