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| Research progress on pharmacological effects of picroside Ⅱ |
| Hits 634 Download times 893 Received:November 03, 2021 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2022.01.23 |
| Key Words
picroside Ⅱ;Rhizoma picrorhizae;pharmacological effects;research development |
| Author Name | Affiliation | E-mail | | CAI Nan | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Traditional Chinese Medicine Research Center, Tasly Holding Group Co. Ltd., Tianjin 300410, China | | | LI Xiaoxuan | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAO Libin | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Zhendong Guangming Pharmaceutical Research Institute, Beijing 100085, China | | | CAO Ningning | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | XIAO Xuefeng | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | kai1219@163.com | | LIU Changxiao | State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300301, China | liuchangxiao@163.com |
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| Abstract
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| Rhizoma picrorhizae, the dried rhizome of Picrorhiza scrophulariiflora Pennell, has the effects of dispelling deficiency heat, eliminating chancre fever and clearing heat and dampness. It has been widely used in clearing deficiency and heat. Rhizoma picrorhizae is mainly produced in Sichuan, Yunnan, Tibet and other places. Currently modern studies have shown that Rhizoma picrorhizae plays an important role in treating liver disease, skin disease and dyspepsia. Picroside Ⅱ is one of the main effective components of the traditional Chinese medicine Rhizoma picrorhizae. It has various pharmacological effects, such as anti-inflammatory, anti-oxidative stress, anti-apoptosis, anti-tumor and anti-fibrosis. Related research progress on pharmacological effects of picroside Ⅱ at home and abroad in recent years are reviewed in this paper, which will provide references for the further development of picroside Ⅱ. |
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