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| Research progress on anti-osteoporotic mechanism of phenethanol glycosides of Cistanche deserticola |
| Hits 658 Download times 433 Received:December 05, 2021 |
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| DOI
10.11656/j.issn.1673-9043.2022.02.27 |
| Key Words
Cistanche deserticola;phenylethanolglycosides;in vivo and in vitro metabolism;anti-osteoporosis;pharmacodynamics;mechanism |
| Author Name | Affiliation | E-mail | | ZHENG Yuling | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Nana | Tianjin Hongri Pharmaceutical Co. Ltd., Tianjin 301617, China | | | FENG Jing | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Hao | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | DING Hui | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | SONG Xinbo | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | songxinbo@tjutcm.edu.cn |
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| Abstract
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| Cistanche deserticola is a kind of precious nourishing medicinal material,known as "desert ginseng",with high medicinal and edible value. Pharmacological studies have confirmed that Cistanche deserticola has anti-oxidation,anti-inflammation,anti-fatigue,anti-aging,anti-osteoporosis,moistening bowel laxative,liver protection,immune regulation and other pharmacological effects,among which phenylethanolside is one of its main active components. In recent years,the anti-osteoporosis effect of phenyleth anol glycosides in Cistanche deserticola has attracted widespread attention. Echinacoside and verbascoside are the representative components,but their anti-osteoporosis mechanism has not been fully elucidated. This article summarizes the literature data of phenethyl alcohol glycosides in Cistanche deserticola at home and abroad,and summarizes the research progress of its metabolic transformation process and products in vivo and in vitro,as well as the pharmacodynamics and mechanism of anti-osteoporosis,in order to provide reference for the experimental research,drug and health food development and clinical application of Cistanche deserticola. |
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