|
| Study on medication rule of Chinese medicine in treating posterior circulation ischemic vertigo based on data mining |
| Hits 693 Download times 430 Received:December 26, 2021 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2022.03.12 |
| Key Words
data mining;posterior circulation ischemia vertigo;medication regularity |
| Author Name | Affiliation | E-mail | | CAI Youde | Jinyang Hospital Affiliated to Guizhou Medical University, Guiyang 550018, China | | | HE Qiansong | The Second Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang 550003, China | 254527635@qq.com | | HU Feiran | The Second Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang 550003, China | | | GUO Qing | The Second Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang 550003, China | | | LI Yuhong | The Second Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang 550003, China | | | FAN Ziyuan | The Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang 712000, China | |
|
| Abstract
|
| [Objective] To explore the rule of using traditional Chinese medicine(TCM) to treat patients with vertigo caused by posterior circulation Ischemia by data mining technique.[Methods] By Literature Search, we collected the related clinical literature from 2004 to 2019, and selected the literature according to the inclusion and exclusion criteria. The prescription contents were recorded in the database, analyze the frequency, frequency analysis and relevance through SPSS 25.0 and IBM SPSS Modeler 18 software, and reveal the medication rule of the circulation ischemic vertigo after treatment.[Results] We screened out 186 related studies, 210 prescriptions of circulation ischemia vertigo were included in the compound prescription of traditional Chinese medicine, involving 173 herbs, and the frequency of use was 2 302 times. Among them, Rhizoma Gastrodiae, Rhizoma Ligusticum Chuanxiong, and Rhizoma Pinelliae are used most frequently. The main drugs are tonifying drugs, blood-activating and stasis-removing drugs, relieving spasm by calming endogenous wind, pacifying liver and subduing yang drugs, exterior-releasing drugs and damp-excreting drugs. The top three syndrome types were deficiency of both qi and blood, syndrome of static blood blocking orifices, syndrome of wind-phlegm invading upward. Apriori algorithm was used for association rules, with support degree ≥ 10%. The top 10 combinations of drug pairs were selected, mainly including tonic drugs, pacifying liver and subduing yang drugs, relieving spasm by calming endogenous wind drugs, blood-activating and stasis-removing drugs, exterior-releasing drugs.[Conclusion] The therapeutic effect of traditional Chinese medicine on posterior circulation ischemia vertigo is significant, and the most prominent rule is tonifying drugs, and the other effects of the herbs for relieving exterior symptoms are the main application, followed by drugs for pacifying liver and subdue yang drugs, extinguishing wind and stopping convulsions drugs, blood-activating and stasis-resolving drugs, and exterior-releasing drugs. The drug group and the drug pair are basically different combinations of drugs for tonifying drugs, acifying liver and subdue yang drugs, extinguishing wind and stopping convulsions drugs, qi-moving drugs, edema-alleviating diuretic, exterior-releasing drugs, blood-activating and stasis-resolving drugs. Syndrome type is closely related to medication. Deficiency is the root cause. Wind, phlegm and blood stasis are the criteria. The principle of tonifying deficiency and reducing diarrhea should be taken to balance the urgency of the specimen. |
|
|
|
|
|
