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| Analysis of medication rules of traditional Chinese medicine patent compound treatment for gallstones based on data mining |
| Hits 585 Download times 267 Received:March 03, 2022 |
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| DOI
10.11656/j.issn.1673-9043.2022.04.19 |
| Key Words
gallstones;ancient and modern medical case cloud platform;association rule;cluster analysis;core network |
| Author Name | Affiliation | E-mail | | HAO Shaodong | Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
Department of Surgery, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing University of Chinese Medicine, Beijing 100039, China | | | LI Yueting | Department of Surgery, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing University of Chinese Medicine, Beijing 100039, China | ly8191@sina.com | | YANG Shanshan | Clinical School of Medicine, Beijing University of Chinese Medicine, Beijing 100029, China | |
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| Abstract
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| [Objective] Based on the ancient and modern medical case cloud platform software, it uses association rules, cluster analysis and other data mining methods to analyze and summarize the medication and compatibility laws of traditional Chinese medicine patent compound treatment of gallstones.[Methods] Use the China National Knowledge Internet patent database to search for Chinese herbal medicines for treating gallstones and exclude single drugs, Chinese herbal extracts, and combination of Chinese and Western medicines, etc., screen and process Chinese patent medicines, establish EXCEL data tables, and apply ancient and modern medical case clouds platform software (V2.2.1) performs statistics and attribute statistics, association rules and cluster analysis of Chinese medicine on the data.[Results] The 274 prescriptions for treating gallstones were screened. The main medications were coldness and bitterness, and the main meridian was liver meridian. The most frequently used Chinese medicines were herba lysimachiae, radix curcumae, bupleurum chinense, endothelium corneum gigeriae galli, capillary artemisia, and Chinese rhubarb etc.; The association rule suggests that the confidence level in the treatment of gallstones were lygodium japonicum-herba lysimachiae, endothelium corneum gigeriae galli-herba lysimachiae, polygonum cuspidatum-herba lysimachiae, bupleurum chinense-herba lysimachiae, capillary artemisia-herba lysimachiae. The 7 types of drugs for treating gallstones are obtained by cluster analysis. The core drug network was composed of 24 traditional Chinese medicines.[Conclusion] The efficacy of the patented traditional Chinese medicine compound medicine for the treatment of gallstones is mainly for clearing away heat and dampness, reducing gallbladder and yellowing, soothing the liver and regulating qi, and purging the bowels, and compatibility is mainly based on clearing heat and dampness, reducing gallbladder and yellowing, soothing the liver and regulating qi. The treatment principle of gallstones is provided, which provides a reference for the clinical treatment of gallstones and the development of traditional Chinese medicine formula. |
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