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Study on correlation between traditional Chinese medicine syndrome types and polysomnography parameters of chronic insomnia
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DOI   10.11656/j.issn.1673-9043.2022.05.07
Key Words   chronic insomnia;traditional Chinese medicine syndrome type;deficiency of heart and spleen;yin deficiency and fire flourishing type;polysomnography
Author NameAffiliationE-mail
TAN Yunxia Hubei University of Chinese Medicine, Wuhan 430065, China  
JI Ke Hubei University of Chinese Medicine, Wuhan 430065, China  
LIU Fugui Hubei University of Chinese Medicine, Wuhan 430065, China  
CHEN Liuyi Hubei University of Chinese Medicine, Wuhan 430065, China  
XIE Ruiliang Hubei University of Chinese Medicine, Wuhan 430065, China  
LIU Ling Hubei University of Chinese Medicine, Wuhan 430065, China
Department of Encephalopathy, Hubei provincial Hospital of Traditional Chinese Medicine, Wuhan 430061, China 
lingliu07199@aliyun.com 
Abstract
    [Objective] To observe the correlation between traditional Chinese medicine (TCM) syndrome types and polysomnography parameters of chronic insomnia.[Methods] The 83 patients with chronic insomnia who came to our outpatient department were observed retrospectively. The general condition data, TCM syndrome characteristics and polysomnography characteristics were summarized.[Results] The incidence rate of chronic insomnia of women was slightly higher than that of men, and the incidence of chronic insomnia was higher over 60 years old. There were 43 cases of yin deficiency and fire excess type and 40 cases of heart-spleen deficiency type. The sleep efficiency of yin deficiency and fire excess type and heart-spleen deficiency type were 66.43% and 61.71% respectively, which were lower than the normal level, but there was no significant difference between the two groups. Sleep process:compared with patients of heart-spleen deficiency type, patients of yin deficiency and fire excess type had longer sleep latency and later sleep phase, but shorter night awakening time, the difference was statistically significant (P<0.05). Sleep structure:compared with the heart-spleen deficiency type, the latency time of rapid eye movement sleep was shortened and the proportion of rapid eye movement sleep(REM) was increased in patients with yin deficiency and fire excess, the difference was statistically significant(P<0.05), while the proportion of slow wave sleep time(SWS) was reduced, and there was no significant statistical difference (P>0.05).[Conclusion] Both heart-spleen deficiency type and yin deficiency and fire excess type are common clinical deficiency syndrome of chronic insomnia. There are significant differences in the parameters of polysomnography between the two syndrome types, suggesting that the parameters of polysomnography can be used as an objective index of traditional Chinese medicine in the prevention and treatment of chronic insomnia and provide reference for later clinical trials.

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