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Research progress of T lymphocytes and their subsets in patients with recurrent spontaneous abortion
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DOI   10.11656/j.issn.1673-9043.2022.05.22
Key Words   recurrent spontaneous abortion;T lymphocytes;immune mechanism
Author NameAffiliationE-mail
YU Tian College of Second Clinical Medicine, Shaanxi University of Chinese Medicine, Xianyang 712046, China  
SHU Hongying The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, China  
YANG Xiaoqi The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, China v515168@126.com 
Abstract
    Recurrent spontaneous abortion(RSA) is a complicated and heterogeneous disease and more than half of the patients have failed to find out the exact cause of the disease, known as unexplained recurrent abortion (URSA), which is thought to be due to immunological mechanisms probably. In recent years, it has been found that T lymphocytes and their subsets are closely related to RSA. However, the mechanisms of immunologic imbalance are unknown. Here, we will review the changes of T-cells in RSA, so as to explore the relationship between the imbalance of immune cells at maternal-fetal interface and RSA.

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