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| Real-world study on the adaptive symptom cluster of Xingnaojing Injection in the treatment of ischemic stroke |
| Hits 1040 Download times 896 Received:August 15, 2022 |
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| DOI
10.11656/j.issn.1673-9043.2022.06.03 |
| Key Words
Xingnaojing Injection;ischemic stroke;Chinese patent medicine;adaptive symptom cluster;real-world study |
| Author Name | Affiliation | E-mail | | FU Gaoshuang | Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China | | | MA Xueyan | College of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China | | | FAN Huanhuan | Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China | | | YAO Yuning | Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China | | | HAO Tong | Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China | | | TUO Tuo | Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China | | | KONG Lingbo | Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China | | | CAO Kegang | Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing 100007, China | kgdoctor@sina.com |
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| Abstract
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| [Objective] Based on real-world medical data,analyze the adaptive symptom cluster of Xingnaojing Injection in the treatment of ischemic stroke. [Methods] A retrospective analysis was carried out using electronic hospital records as data. The cases were divided into effective group and ineffective group according to the changes in the condition before and after treatment,and the related indexes of adaptive symptom cluster were determined by χ2 test and binary logistic regression analysis,and the results were visualized as a nomogram. [Results] Red tongue and slippery pulse had a positive effect on the curative effect of Xingnaojing Injection,and patients with this feature were more effective. Fatigue,pale complexion,and less tongue coating have a negative impact on the curative effect of Xingnaojing Injection,and patients with this feature had poor effectiveness. [Conclusion] Clarifying the clinically adaptive symptom clusters of Chinese patent medicines can guide physicians in the rational use of drugs,and the use of real-world medical data can become a model for studying the clinically adaptive symptom clusters of Chinese patent medicines. |
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